MacroGenics is a clinical-stage biopharmaceutical company focused on discovering and developing innovative monoclonal antibod ... y-based therapeutics for the treatment of cancer. The Company generates its pipeline of product candidates primarily from its proprietary suite of next-generation antibody-based technology platforms, which have applicability across broad therapeutic domains. The combination of MacroGenics' technology platforms and protein engineering expertise has allowed the Company to generate promising product candidates and enter into several strategic collaborations with global pharmaceutical and biotechnology companies. MacroGenics’ most advanced program is margetuximab, an Fc-optimized monoclonal antibody that targets HER2, and is being investigated in the SOPHIA study, a Phase 3, randomized, multi-center clinical trial in patients with metastatic breast cancer. read more