Sleep with Art... 21c Museum Hotel in Louisville, KY is more than just a place to spend the night – a 90-room boutique hotel, ... contemporary art museum, award-winning restaurant, and cultural civic center. Nestled in the heart of Museum Row, 21c’s guests to enjoy modern Southern hospitality and accessible luxury, while exploring the work of 21st century artists. 21c Museum Hotel:: Voted #1 Hotel in U.S. and #6 in World in Condé Nast Traveler’s Readers’ Choice Awards 2009. “An innovative concept with strong execution and prompt and enthusiastic service. Allow plenty of time for exploring 21c’s less obvious exhibition spaces, including, as the bellman suggested, those infamous artistic restrooms.” —Pableaux Johnson, The New York Times read more